Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.717583?ai=1lir&mi=3s94u5&af=R
Miyerkules, Oktubre 31, 2012
Mid- to long-term factors influencing functional status of people affected by lower-limb amputation associated with hemiparesis due to stroke
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
The process of re-engagement in personally valued activities during the 2 years following stroke
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.691936?ai=1lir&mi=3s94u5&af=R
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Dynamic Essentials Loyalty is the Key
News from DE
Webster's Dictionary defines the word "loyalty" as: the state or quality of being loyal... feeling of faithfulness or alliance."
We could use and think of many illustrations of loyalty such as loyalty of a dog to its master... loyalty of a spouse to each other... loyalty to your team, family or country, etc. But probably the best...
This is a planetchiropractic content summary feed. Visit www.planetchiropractic.com for complete content, links, and related media. - Cheers! 
Webster's Dictionary defines the word "loyalty" as: the state or quality of being loyal... feeling of faithfulness or alliance."
We could use and think of many illustrations of loyalty such as loyalty of a dog to its master... loyalty of a spouse to each other... loyalty to your team, family or country, etc. But probably the best...
This is a planetchiropractic content summary feed. Visit www.planetchiropractic.com for complete content, links, and related media. - Cheers!
Practical research-based guidance for motor imagery practice in neurorehabilitation
Disability and Rehabilitation, Volume 34, Issue 25, Page 2192-2200, December 2012.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.676703?ai=1lir&mi=3s94u5&af=R
Is walking faster or walking farther more important to persons with chronic stroke?
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.717575?ai=1lir&mi=3s94u5&af=R
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Body mass index patterns following dysvascular lower extremity amputation
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-7, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.726690?ai=1lir&mi=3s94u5&af=R
Table of Contents
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Can Quality of Care Indicators Measure Quality of Care?
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Dale C. Strasser, Judith A. Falconer, Jay M. Uomoto
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Dale C. Strasser, Judith A. Falconer, Jay M. Uomoto
Martes, Oktubre 30, 2012
Multi-professional and multi-dimensional group education – a key to action in elderly persons
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.697249?ai=1lir&mi=3s94u5&af=R
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Why Hot, Humid Air Triggers Symptoms in Patients with Mild Asthma
May is asthma awareness month, and with summer right around the corner, a study shows that doctors may be closer to understanding why patients with mild asthma have such difficulty breathing during hot, humid weather. The study, appearing in the June print issue of the American Journal of Respiratory and Critical Care Medicine, found that patients who inhaled an asthma drug before breathing in hot, humid air were able to prevent airway constriction that volunteers without asthma did not experience in the same environment.
Ipratropium, a drug occasionally used for asthma, prevents airway muscle contraction and increases airflow to the lungs. Its success in combating the air temperature response suggests that hot, humid air triggers asthma symptoms by activating airway sensory nerves that are sensitive to an increase in temperature.
“We know that breathing cold, dry air induces airway constriction in asthmatics,” said Don Hayes, MD, medical director of the Lung and Heart-Lung Transplant Program at Nationwide Children’s Hospital. “But the effects that temperature increases have on airway function in these patients are generally overlooked. We know very little about the mechanisms that cause symptoms when asthmatic patients are exposed to hot, humid air.”
Ipratropium, a drug occasionally used for asthma, prevents airway muscle contraction and increases airflow to the lungs. Its success in combating the air temperature response suggests that hot, humid air triggers asthma symptoms by activating airway sensory nerves that are sensitive to an increase in temperature.
“We know that breathing cold, dry air induces airway constriction in asthmatics,” said Don Hayes, MD, medical director of the Lung and Heart-Lung Transplant Program at Nationwide Children’s Hospital. “But the effects that temperature increases have on airway function in these patients are generally overlooked. We know very little about the mechanisms that cause symptoms when asthmatic patients are exposed to hot, humid air.”
Source: http://www.health.am/allergies/more/triggers-symptoms-in-patients-with-mild-asthma/
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Effectiveness of Thermal Stimulation for the Moderately to Severely Paretic Leg After Stroke: Serial Changes at One-Year Follow-Up
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Chung-Chao Liang, Tsung-Cheng Hsieh, Chun-Hsiang Lin, Yu-Chun Wei, Jung Hsiao, Jia-Ching Chen
Liang C-C, Hsieh T-C, Lin C-H, Wei Y-C, Hsiao J, Chen J-C. Effectiveness of thermal stimulation for the moderately to severely paretic leg after stroke: serial changes at one-year follow-up. Objective To evaluate the serial changes of long-term effects of thermal stimulation (TS) on acute stroke patients. Design A prospective study with follow-up at 3, 6, and 12 months after TS to assess motor and balance function of the paretic leg of acute stroke patients. Setting A general hospital rehabilitation department. Participants Poststroke patients (N=30) with moderate to severe impairment of leg function. Interventions In addition to receiving standard rehabilitation, eligible patients were randomly assigned to a TS group (5 thermal stimulations per week for 6wk) or a control group (3 consultations per week for 6wk). Main Outcome Measures Fugl-Meyer lower extremity score, Medical Research Council Scale for the Lower Extremity, Berg Balance Scale, Modified Motor Assessment Scale, Functional Ambulation Classification, and Barthel Index were administered at baseline, after 4 and 6 weeks of treatment, and at the 3-, 6-, and 12-month follow-up. Results No significant differences were found between the 2 groups at baseline. After TS, the Fugl-Meyer lower extremity score, Medical Research Council Scale for the Lower Extremity, Modified Motor Assessment Scale, and Functional Ambulation Classification were significantly better in the TS group, and the effects persisted for 3 months (P <.05). Significant differences were found between the 2 groups for the Berg Balance Scale and Barthel Index only at the 3-month follow-up (P <.05). However, all the effects except for the Fugl-Meyer lower extremity score had disappeared at the 6-month follow-up (P >.05). Conclusions The long-term benefits of TS for patients with acute stroke may be sustained for 3 months but disappear by the 6-month and 1-year follow-up.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Chung-Chao Liang, Tsung-Cheng Hsieh, Chun-Hsiang Lin, Yu-Chun Wei, Jung Hsiao, Jia-Ching Chen
Differences in habitual physical activity levels of young people with cerebral palsy and their typically developing peers: a systematic review
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.715721?ai=1lir&mi=3s94u5&af=R
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Changes in Objectively Measured Physical Activity (Performance) After Epidural Steroid Injection for Lumbar Spinal Stenosis
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Christy C. Tomkins-Lane, Justin Conway, Charles Hepler, Andrew J. Haig
Tomkins-Lane CC, Conway J, Hepler C, Haig AJ. Changes in objectively measured physical activity (performance) after epidural steroid injection for lumbar spinal stenosis. Objective To examine changes in objectively measured physical activity (performance) at 1 week following epidural steroid injection for lumbar spinal stenosis. Design Prospective cohort. Setting University spine program. Participants Individuals (N=17) who were undergoing fluoroscopically guided epidural steroid injection for symptomatic lumbar spinal stenosis (mean age ± SD, 70.1±6.7; 47% women). Intervention Fluoroscopically guided epidural injection. Main Outcome Measure(s) The 2 primary outcomes, measured with accelerometers, were total activity (performance) measured over 7 days and maximum continuous activity (capacity). Walking capacity was also assessed with the Self-Paced Walking Test, and subjects completed the Oswestry Disability Index, Swiss Spinal Stenosis Questionnaire, Medical Outcomes Study 36-Item Short-Form Health Survey, visual analog pain scales, and body diagrams. Results At 1 week postinjection, 58.8% of the subjects demonstrated increased total activity and 53% had increased maximum continuous activity, although neither change was statistically significant. Significant improvements were observed in a number of the self-report instruments, including the Physical Function Scale of the Swiss Spinal Stenosis Questionnaire, general health (Medical Outcomes Study 36-Item Short-Form Health Survey), role-limitation emotional (Medical Outcomes Study 36-Item Short-Form Health Survey), leg pain intensity (visual analog pain scales), and presence of leg weakness. Conclusions While patients perceived improvements in pain and function following injection, these improvements were not reflected in significant changes in performance or capacity. Future studies will continue to find value in subjective measures of pain and quality of life. However, with modern technology, performance is no longer a subjective variable. Use of activity monitors to objectively measure performance can result in more rigorous validation of treatment effects, while simultaneously highlighting the potential need for additional postinjection rehabilitation aimed at improving performance.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Christy C. Tomkins-Lane, Justin Conway, Charles Hepler, Andrew J. Haig
chiropractor chiropractic back pain solution neck pain solution
ICF-CY based assessment tool for children with autism
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.705946?ai=1lir&mi=3s94u5&af=R
Lunes, Oktubre 29, 2012
The International Classification of Functioning (ICF) Core Set for breast cancer from the perspective of women with the condition
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.707742?ai=1lir&mi=3s94u5&af=R
A phenomenological approach to psychoprosthetics
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-7, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.708819?ai=1lir&mi=3s94u5&af=R
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Practical research-based guidance for motor imagery practice in neurorehabilitation
Disability and Rehabilitation, Volume 34, Issue 25, Page 2192-2200, December 2012.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.676703?ai=1lir&mi=3s94u5&af=R
A systematic review of disability awareness interventions for children and youth
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-24, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.702850?ai=1lir&mi=3s94u5&af=R
A qualitative study of the childbearing experience of women living with multiple sclerosis
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-6, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.717581?ai=1lir&mi=3s94u5&af=R
Interdisciplinary communication in inpatient rehabilitation facility: evidence of under-documentation of spatial neglect after stroke
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-6, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.717585?ai=1lir&mi=3s94u5&af=R
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Sexuality and occupational therapy in Ireland – a case of ambivalence?
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.688920?ai=1lir&mi=3s94u5&af=R
Successfully performing a university student’s role despite disabilities: challenges of an inclusive environment and appropriate task modification
Disability and Rehabilitation, Volume 34, Issue 25, Page 2201-2206, December 2012.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.680648?ai=1lir&mi=3s94u5&af=R
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Linggo, Oktubre 28, 2012
Rehabilitation outcome of post-acute lower limb geriatric amputees
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-7, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.690818?ai=1lir&mi=3s94u5&af=R
What hypoallergenic dog?
The allergy-friendly dog may be little more than wishful thinking, a new study of Labradoodles and other allegedly hypoallergenic breeds suggests.
In fact, scientists found that “hypoallergenic” canines had more allergy-causing protein in their fur than did dogs without the label. And the air in their owners’ homes contained no less of the allergenic protein.
“The term ‘hypoallergenic’ is a misnomer that is not evidence based,” they conclude in their report, published this week in the Journal of Allergy and Clinical Immunology.
About one in five people in Western countries is allergic to dogs. But according to countless Internet pages, aspiring dog owners can get around runny noses and itchy eyes if they choose the right breed. There’s the Poodle, for example, the Spanish Water Dog and the Labradoodle, a mix between a Labrador Retriever and a Poodle.
In fact, scientists found that “hypoallergenic” canines had more allergy-causing protein in their fur than did dogs without the label. And the air in their owners’ homes contained no less of the allergenic protein.
“The term ‘hypoallergenic’ is a misnomer that is not evidence based,” they conclude in their report, published this week in the Journal of Allergy and Clinical Immunology.
About one in five people in Western countries is allergic to dogs. But according to countless Internet pages, aspiring dog owners can get around runny noses and itchy eyes if they choose the right breed. There’s the Poodle, for example, the Spanish Water Dog and the Labradoodle, a mix between a Labrador Retriever and a Poodle.
Source: http://www.health.am/allergies/more/what-hypoallergenic-dog/
“But I know what works” – patients’ experience of spinal cord injury neuropathic pain management
Disability and Rehabilitation, Volume 34, Issue 25, Page 2139-2147, December 2012.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.676146?ai=1lir&mi=3s94u5&af=R
A pilot randomized controlled trial of an early multidisciplinary model to prevent disability following traumatic injury
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-15, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.721047?ai=1lir&mi=3s94u5&af=R
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Merck’s once-a-week diabetes drug effective in clinical study
An experimental once-a-week drug for type 2 diabetes being developed by Merck & Co proved effective in lowering blood sugar levels in a mid-stage clinical trial, according to data presented on Wednesday.
The pill, known as MK-3102, is from the same class of medicines as Merck’s successful daily diabetes drug Januvia, known as DPP-4 inhibitors.
The 685-patient study tested MK-3102 at five doses - ranging from 0.25 milligram to 25 mg - against a placebo, with the primary goal being reduction in A1c, a common measure of blood sugar.
After 12 weeks of treatment with the Merck drug, A1c was reduced 0.71 percent at 25 mg, 0.67 percent at 10 mg, 0.49 percent at 3 mg, 0.5 percent with 1 mg, and 0.28 percent for the lowest 0.25 mg dose. The reductions compared with placebo for all doses were deemed to be statistically significant, according to Merck, which presented the data on Wednesday at the European Association for the Study of Diabetes (EASD) meeting in Berlin.
The pill, known as MK-3102, is from the same class of medicines as Merck’s successful daily diabetes drug Januvia, known as DPP-4 inhibitors.
The 685-patient study tested MK-3102 at five doses - ranging from 0.25 milligram to 25 mg - against a placebo, with the primary goal being reduction in A1c, a common measure of blood sugar.
After 12 weeks of treatment with the Merck drug, A1c was reduced 0.71 percent at 25 mg, 0.67 percent at 10 mg, 0.49 percent at 3 mg, 0.5 percent with 1 mg, and 0.28 percent for the lowest 0.25 mg dose. The reductions compared with placebo for all doses were deemed to be statistically significant, according to Merck, which presented the data on Wednesday at the European Association for the Study of Diabetes (EASD) meeting in Berlin.
Source: http://www.health.am/db/more/diabetes-drug-effective-in-clinical-study/
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Successfully performing a university student’s role despite disabilities: challenges of an inclusive environment and appropriate task modification
Disability and Rehabilitation, Volume 34, Issue 25, Page 2201-2206, December 2012.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.680648?ai=1lir&mi=3s94u5&af=R
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Sabado, Oktubre 27, 2012
The course of health-related quality of life of preschool children with cerebral palsy
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.705947?ai=1lir&mi=3s94u5&af=R
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Sonoelastographic Evaluation of Medial Gastrocnemius Muscles Intrinsic Stiffness After Rehabilitation Therapy With Botulinum Toxin A Injection in Spastic Cerebral Palsy
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Gi-Young Park, Dong Rak Kwon
Park G-Y, Kwon DR. Sonoelastographic evaluation of medial gastrocnemius muscles intrinsic stiffness after rehabilitation therapy with botulinum toxin A injection in spastic cerebral palsy. Objective To investigate intrinsic stiffness changes using real-time sonoelastography (RTS) in the medial gastrocnemius muscle (GCM) after rehabilitation therapy with botulinum toxin type A (BTA) injection in spastic cerebral palsy (CP). Design Prospective study using ultrasonography and RTS. Setting An inpatient rehabilitation clinic. Participants Children (N=17) with spastic CP (mean age, 57±22y, age range, 26–110mo). Intervention Rehabilitation therapy and intramuscular injection of BTA in both medial and lateral GCMs. Main Outcome Measures RTS was obtained on the medial GCM, and the elastic pattern of the medial GCM was graded from RTS 1 (purple to green: soft) to RTS 4 (red: stiff) on the basis of color-scaled RTS. RTS score, color histogram, Modified Ashworth Scale (MAS) score of the ankle plantar flexor muscles, and Gross Motor Function Measure (GMFM) score were obtained before intervention and 4 weeks after intervention. The correlations among RTS score, GMFM, and MAS score were determined. Intrarater reliability was also evaluated. Results Before and at 4 weeks after intervention, the mean RTS score decreased from 3.4 to 1.5 (P <.05), median red pixel intensity decreased from 112.5 to 101.3 (P <.05), median blue pixel intensity increased from 82.6 to 90.4 (P <.05), mean MAS score of the ankle decreased from 2.7 to 1.3 (P <.05), and mean GMFM score increased from 54.55% to 62.32%. Significant correlations were observed between the RTS score and the MAS score. Intrarater reliability was high. Conclusions Our results suggest that more information about the change of spastic muscle in CP after rehabilitation treatment with BTA may be gained by estimating muscle stiffness using RTS combined with clinical scale measurements.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Gi-Young Park, Dong Rak Kwon
Getting the pain right: how low back pain patients manage and express their pain experiences
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.709302?ai=1lir&mi=3s94u5&af=R
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Randomized controlled trial of a self-management intervention in persons with spinal cord injury: design of the HABITS (Healthy Active Behavioural IntervenTion in SCI) study
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.718406?ai=1lir&mi=3s94u5&af=R
Identification of core functioning features for assessment and intervention in Autism Spectrum Disorders
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.690494?ai=1lir&mi=3s94u5&af=R
The perceived benefits and barriers of sport in spinal cord injured individuals: a qualitative study
Disability and Rehabilitation, Volume 34, Issue 24, Page 2061-2070, December 2012.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.669020?ai=1lir&mi=3s94u5&af=R
Request for Proposals 2015 Archives Supplement 1
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Biyernes, Oktubre 26, 2012
Validity of the Intelligent Device for Energy Expenditure and Activity Accelerometry System for Quantitative Gait Analysis in Patients With Hip Osteoarthritis
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Julia F. Item-Glatthorn, Nicola C. Casartelli, Jeannette Petrich-Munzinger, Urs K. Munzinger, Nicola A. Maffiuletti
Item-Glatthorn JF, Casartelli NC, Petrich-Munzinger J, Munzinger UK, Maffiuletti NA. Validity of the Intelligent Device for Energy Expenditure and Activity accelerometry system for quantitative gait analysis in patients with hip osteoarthritis. Objective To evaluate the concurrent validity of an accelerometry-based system (Intelligent Device for Energy Expenditure and Activity) with a criterion instrument (Gaitrite) for the evaluation of spatiotemporal gait variables in orthopedic patients. Design Validity study. Setting Research laboratory in an orthopedic hospital. Participants Men with unilateral hip osteoarthritis (N=26; mean age ± SD, 54±9y). Interventions Not applicable. Main Outcome Measures Patients were asked to walk at normal and fast velocities while gait cycle, swing, double support, step length, cadence, and speed were concomitantly recorded with the 2 instruments. Concurrent criterion-related validity was examined using intraclass correlation coefficients and Bland-Altman limits of agreement. Results Intraclass correlation coefficients were acceptable for all gait parameters (range, .815–.997), except step length (.783). Limits of agreement were low for gait cycle, swing, and cadence, though relatively high for double support, step length, and speed. A significant bias between the 2 measuring instruments was consistently observed. Conclusions In patients with hip osteoarthritis, quantitative gait analysis with the IDEEA accelerometry system was satisfactory for the main temporal gait parameters, while double support, step length, and walking speed quantifications were invalid. The IDEEA system should be used with caution, and modifications of the system are recommended for improved use in clinical practice and research.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Julia F. Item-Glatthorn, Nicola C. Casartelli, Jeannette Petrich-Munzinger, Urs K. Munzinger, Nicola A. Maffiuletti
Addison’s disease
Alternative names
Adrenocortical hypofunction; Chronic adrenocortical insufficiency; Adrenal insufficiency
Definition
Addison’s disease is a hormone deficiency caused by damage to the outer layer of the adrenal gland (adrenal cortex).
see Addison’s disease in Encyclopedia.
Adrenocortical hypofunction; Chronic adrenocortical insufficiency; Adrenal insufficiency
Definition
Addison’s disease is a hormone deficiency caused by damage to the outer layer of the adrenal gland (adrenal cortex).
see Addison’s disease in Encyclopedia.
Source: http://www.health.am/diseases/more/addisons_disease/
Reliability and Validity of a Low Load Endurance Strength Test for Upper and Lower Extremities in Patients With Fibromyalgia
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Diego MunguÃa-Izquierdo, Alejandro Legaz-Arrese
MunguÃa-Izquierdo D, Legaz-Arrese A. Reliability and validity of a low load endurance strength test for upper and lower extremities in patients with fibromyalgia. Objective To evaluate the reliability, standard error of the mean (SEM), clinical significant change, and known group validity of 2 assessments of endurance strength to low loads in patients with fibromyalgia syndrome (FS). Design Cross-sectional reliability and comparative study. Setting University Pablo de Olavide, Seville, Spain. Participants Middle-aged women with FS (n=95) and healthy women (n=64) matched for age, weight, and body mass index (BMI) were recruited for the study. Interventions Not applicable. Main Outcome Measures The endurance strength to low loads tests of the upper and lower extremities and anthropometric measures (BMI) were used for the evaluations. The differences between the readings (tests 1 and 2) and the SDs of the differences, intraclass correlation coefficient (ICC) model (2,1), 95% confidence interval for the ICC, coefficient of repeatability, intrapatient SD, SEM, Wilcoxon signed-rank test, and Bland-Altman plots were used to examine reliability. A Mann-Whitney U test was used to analyze the differences in test values between the patient group and the control group. We hypothesized that patients with FS would have an endurance strength to low loads performance in lower and upper extremities at least twice as low as that of the healthy controls. Results Satisfactory test-retest reliability and SEMs were found for the lower extremity, dominant arm, and nondominant arm tests (ICC=.973–.979; P <.001; SEMs=1.44–1.66 repetitions). The differences in the mean between the test and retest were lower than the SEM for all performed tests, varying from −.10 to .29 repetitions. No significant differences were found between the test and retest (P >.05 for all). The Bland-Altman plots showed 95% limits of agreement for the lower extremity (4.7 to –4.5), dominant arm (3.8 to –4.4), and nondominant arm (3.9 to –4.1) tests. The endurance strength to low loads test scores for the patients with FS were 4-fold lower than for the controls in all performed tests (P <.001 for all). Conclusions The endurance strength to low loads tests showed good reliability and known group validity and can be recommended for evaluating endurance strength to low loads in patients with FS. For individual evaluation, however, an improved score of at least 4 and 5 repetitions for the upper and lower extremities, respectively, was required for the differences to be considered as substantial clinical change. Patients with FS showed impaired endurance strength to low loads performance when compared with the general population.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Diego MunguÃa-Izquierdo, Alejandro Legaz-Arrese
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Corrections
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Masthead
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 11
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Huwebes, Oktubre 25, 2012
Asthma symptoms could be aggravated by imbalance problems
Vienna, Austria: Asthma patients could be at a higher risk of worsening symptoms due to problems with their balance, according to new research.
The study will be presented today (2 September 2012) at the European Respiratory Society’s Annual Congress in Vienna.
Researchers aimed to assess the link between asthma, anxiety and balance. Anxiety and imbalance are closely related. Muscles and joints are controlled by signals from the brain, which are, in turn, sent from stimuli from the eyes and inner ear. This function is also controlled by the limbic system in the brain, which is additionally responsible for emotions, such as anxiety.
It is well known that anxiety can exacerbate asthma symptoms, yet there has been little research into whether balance abnormalities also have a negative influence on asthmatics.
The study will be presented today (2 September 2012) at the European Respiratory Society’s Annual Congress in Vienna.
Researchers aimed to assess the link between asthma, anxiety and balance. Anxiety and imbalance are closely related. Muscles and joints are controlled by signals from the brain, which are, in turn, sent from stimuli from the eyes and inner ear. This function is also controlled by the limbic system in the brain, which is additionally responsible for emotions, such as anxiety.
It is well known that anxiety can exacerbate asthma symptoms, yet there has been little research into whether balance abnormalities also have a negative influence on asthmatics.
Source: http://www.health.am/allergies/more/asthma-symptoms-could-be-aggravated/
Type 2 diabetes may increase the risk of Barrett’s esophagus
Patients with Type 2 Diabetes may face an increased risk for Barrett’s Esophagus (BE), regardless of other risk factors including smoking, alcohol consumption, obesity and gastroesophageal reflux disease (GERD), according to research unveiled today at the American College of Gastroenterology’s (ACG) 77th Annual Scientific meeting in Las Vegas.
The study, “Diabetes Mellitus Increases the Risk of Barrett’s Esophagus: Results from A Large Population Based Control Case Study,” suggests that, “if you have diabetes, your risk for Barrett’s esophagus (BE) may be almost doubled ,” said co-investigator, Prasad G. Iyer, M.D., of the Mayo Clinic College of Medicine. He said this risk may be higher in men with diabetes likely because men tend to carry more fat in the abdomen compared to women who tend to carry weight around the hips and thighs.
Type 2 diabetes is the most is the most form of diabetes, with millions of Americans living with the disease. Barrett’s esophagus is a condition in which the tissue lining the esophagus is replaced by tissue that is similar to the lining of the intestine. No signs or symptoms are associated with Barrett’s esophagus but it is commonly found in people with GERD. About 5 to 10 percent of patients with chronic GERD will develop Barrett’s esophagus.
Performing a population-based control study using the United Kingdom’s General Practice Research Database (GPRD) (a primary care database containing more than 8 million patients), the researchers identified 14,245 Barrett’s esophagus cases and 70,361 controls without Barrett’s esophagus.
The study, “Diabetes Mellitus Increases the Risk of Barrett’s Esophagus: Results from A Large Population Based Control Case Study,” suggests that, “if you have diabetes, your risk for Barrett’s esophagus (BE) may be almost doubled ,” said co-investigator, Prasad G. Iyer, M.D., of the Mayo Clinic College of Medicine. He said this risk may be higher in men with diabetes likely because men tend to carry more fat in the abdomen compared to women who tend to carry weight around the hips and thighs.
Type 2 diabetes is the most is the most form of diabetes, with millions of Americans living with the disease. Barrett’s esophagus is a condition in which the tissue lining the esophagus is replaced by tissue that is similar to the lining of the intestine. No signs or symptoms are associated with Barrett’s esophagus but it is commonly found in people with GERD. About 5 to 10 percent of patients with chronic GERD will develop Barrett’s esophagus.
Performing a population-based control study using the United Kingdom’s General Practice Research Database (GPRD) (a primary care database containing more than 8 million patients), the researchers identified 14,245 Barrett’s esophagus cases and 70,361 controls without Barrett’s esophagus.
Source: http://www.health.am/db/more/type-2-diabetes-may-increase-the-risk/
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Needs, priorities, and desired rehabilitation outcomes of family members of young adults who have had a stroke: findings from a phenomenological study
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-10, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.711895?ai=1lir&mi=3s94u5&af=R
Career readiness, developmental work personality and age of onset in young adult central nervous system survivors
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.703754?ai=1lir&mi=3s94u5&af=R
“It’s a Hidden Issue”: Exploring the experiences of women with HIV-associated neurocognitive challenges using a disability framework
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-11, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.687029?ai=1lir&mi=3s94u5&af=R
Miyerkules, Oktubre 24, 2012
Multi-professional and multi-dimensional group education – a key to action in elderly persons
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.697249?ai=1lir&mi=3s94u5&af=R
Recommended Site chiropractor chiropractic back pain solution
Conceptualizing belonging
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-7, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.717584?ai=1lir&mi=3s94u5&af=R
Are gait and mobility measures responsive to change following botulinum toxin injections in adults with lower limb spasticity?
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.717579?ai=1lir&mi=3s94u5&af=R
Parker University Receives Oklahaven Golden Heart Award
Parker Chiropractic News
DALLAS -- Oklahaven Children's Chiropractic Center, a non-profit organization that treats sick and disabled children through chiropractic care, recently honored Parker University with the Golden Heart Award as the chiropractic institution that raised the most funds during Oklahaven's 2012 Have-a-Heart Campaign. Each year,...
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DALLAS -- Oklahaven Children's Chiropractic Center, a non-profit organization that treats sick and disabled children through chiropractic care, recently honored Parker University with the Golden Heart Award as the chiropractic institution that raised the most funds during Oklahaven's 2012 Have-a-Heart Campaign. Each year,...
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The impact of rehabilitative services in the lives of adults and children with disabilities, in low-income and middle-income countries: an assessment of the quality of the evidence
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-10, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.705949?ai=1lir&mi=3s94u5&af=R
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Prevalence and Impact of Chronic Musculoskeletal Ankle Disorders in the Community
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 10
Claire E. Hiller, Elizabeth J. Nightingale, Jacqueline Raymond, Sharon L. Kilbreath, Joshua Burns, Deborah A. Black, Kathryn M. Refshauge
Hiller CE, Nightingale EJ, Raymond J, Kilbreath SL, Burns J, Black DA, Refshauge KM. Prevalence and impact of chronic musculoskeletal ankle disorders in the community. Objective To determine the point prevalence of chronic musculoskeletal ankle disorders in the community. Design Cross-sectional stratified (metropolitan vs regional) random sample. Setting General community. Participants Population-based computer-aided telephone survey of people (N=2078) aged 18 to 65 years in New South Wales, Australia. Of those contacted, 751 participants provided data. Interventions Not applicable. Main Outcome Measures Point prevalence for no history of ankle injury or chronic ankle problems (no ankle problems), history of ankle injury without residual problems, and chronic ankle disorders. Chronic musculoskeletal ankle disorders due to ankle sprain, fracture, arthritis, or other disorder compared by chi-square test for the presence of pain, weakness, giving way, swelling and instability, activity limitation, and health care use in the past year. Results There were 231 (30.8%) participants with no ankle problems, 342 (45.5%) with a history of ankle injury but no chronic problems, and 178 (23.7%) with chronic ankle disorders. The major component of chronic ankle disorders was musculoskeletal disorders (n=147, 19.6% of the total sample), most of which were due to ankle injury (n=117, 15.6% of the total). There was no difference among the arthritis, fracture, sprain, and other groups in the prevalence of the specific complaints, or health care use. Significantly more participants with arthritis had to limit activity than in the sprain group (Chi-square test, P =.035). Conclusions Chronic musculoskeletal ankle disorders affected almost 20% of the Australian community. The majority were due to a previous ankle injury, and most people had to limit or change their physical activity because of the ankle disorder.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 10
Claire E. Hiller, Elizabeth J. Nightingale, Jacqueline Raymond, Sharon L. Kilbreath, Joshua Burns, Deborah A. Black, Kathryn M. Refshauge
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Mapping patients’ experiences after stroke onto a patient-focused intervention framework
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.702844?ai=1lir&mi=3s94u5&af=R
Martes, Oktubre 23, 2012
Exercise Adherence to Pelvic Floor Muscle Strengthening Is Not a Significant Predictor of Symptom Reduction for Women With Urinary Incontinence
Publication year: 2012
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 10
Hsiu-Chuan Hung, Shu-Yun Chih, Ho-Hsiung Lin, Jau-Yih Tsauo
Hung H-C, Chih S-Y, Lin H-H, Tsauo J-Y. Exercise adherence to pelvic floor muscle strengthening is not a significant predictor of symptom reduction for women with urinary incontinence. Objective To explore the predictors of treatment effectiveness for women with urinary incontinence (UI) receiving pelvic floor muscle (PFM) strengthening. Design Four-month cohort study. Setting Laboratory. Participants Volunteers (N=68; mean age ± SD, 50.5±6.0y) with UI. Intervention Four-month daily PFM strengthening exercise program at home. Main Outcome Measures Outcome measures included self-reported improvement, Severity Index score, 3-days diary, strength of PFM, and quality of life. The participants' recall of the amount of exercise after the 4-month exercise period was used to assess the exercise adherence. Results Fifty-one (75%) of 68 women reported that their condition improved after 4 months of exercise. There were significant reductions in Severity Index score, number of voidings per day, number of leakages per day, and impact on quality of life (P <.05). In addition, the score of PFM strength was significantly improved (P =.001). There were no significant correlations between the change score of the Severity Index and age, body mass index, parity, type of UI, duration of UI, menopausal status, and amount of exercise (all P >.10). Multiple regression analysis revealed that initial severity of symptoms and improvement of PFM strength predicted 51.3% of variance in 4-month exercise effectiveness (change score of the Severity Index). Conclusions The effectiveness of the 4-month PFM strengthening program was influenced by the severity of symptoms and the improvement score of PFM strength instead of exercise adherence. Women who had more significant symptoms of leakage (higher score on the Severity Index at baseline) and who had more improvement of PFM strength showed more improvement of symptoms after PFM strengthening.
Source:Archives of Physical Medicine and Rehabilitation, Volume 93, Issue 10
Hsiu-Chuan Hung, Shu-Yun Chih, Ho-Hsiung Lin, Jau-Yih Tsauo
WCCS Regional Conference Called Game Changer
Life West News
The First WCCS Regional Conference Hosted At Life West Called A 'Game-Changer'
Hayward, California - On May 3, 2012, Life Chiropractic College West hosted the first World Congress of Chiropractic Students (WCCS) regional event which ran over the course of four days. Chiropractic students from 13 schools in four countries and two...
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The First WCCS Regional Conference Hosted At Life West Called A 'Game-Changer'
Hayward, California - On May 3, 2012, Life Chiropractic College West hosted the first World Congress of Chiropractic Students (WCCS) regional event which ran over the course of four days. Chiropractic students from 13 schools in four countries and two...
This is a planetchiropractic content summary feed. Visit www.planetchiropractic.com for complete content, links, and related media. - Cheers!
Using the ICF to develop the capability-oriented database of persons with disabilities: a case study in Nakornpanom province, Thailand
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.720351?ai=1lir&mi=3s94u5&af=R
Investigation of quality of life in mothers of children withcerebral palsy in Iran: association with socio-economic status,marital satisfaction and fatigue
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-6, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.708818?ai=1lir&mi=3s94u5&af=R
Lack of sleep leads to insulin resistance in teens
A new study suggests that increasing the amount of sleep that teenagers get could improve their insulin resistance and prevent the future onset of diabetes.
“High levels of insulin resistance can lead to the development of diabetes,” said lead author Karen Matthews, PhD, of the University of Pittsburgh Department of Psychiatry. “We found that if teens that normally get six hours of sleep per night get one extra hour of sleep, they would improve insulin resistance by 9 percent.”
The study, appearing in the October issue of the journal SLEEP, tracked the sleep duration and insulin resistance levels of 245 healthy high school students. Participants provided a fasting blood draw, and they kept a sleep log and wore a wrist actigraph for one week during the school year. Sleep duration based on actigraphy averaged 6.4 hours over the week, with school days significantly lower than weekends.
Results show that higher insulin resistance is associated with shorter sleep duration independent of race, age, gender, waist circumference, and body mass index. According to Matthews, the study is the only one in healthy adolescents that shows a relationship between shorter sleep and insulin resistance that is independent of obesity.
“High levels of insulin resistance can lead to the development of diabetes,” said lead author Karen Matthews, PhD, of the University of Pittsburgh Department of Psychiatry. “We found that if teens that normally get six hours of sleep per night get one extra hour of sleep, they would improve insulin resistance by 9 percent.”
The study, appearing in the October issue of the journal SLEEP, tracked the sleep duration and insulin resistance levels of 245 healthy high school students. Participants provided a fasting blood draw, and they kept a sleep log and wore a wrist actigraph for one week during the school year. Sleep duration based on actigraphy averaged 6.4 hours over the week, with school days significantly lower than weekends.
Results show that higher insulin resistance is associated with shorter sleep duration independent of race, age, gender, waist circumference, and body mass index. According to Matthews, the study is the only one in healthy adolescents that shows a relationship between shorter sleep and insulin resistance that is independent of obesity.
Source: http://www.health.am/db/more/insulin-resistance-in-teens/
Implementation of ICF in goal setting in rehabilitation of children with chronic disabilities at Beitostolen Healthsports Centre
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-8, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.690499?ai=1lir&mi=3s94u5&af=R
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How policy on employee involvement in work reintegration can yield its opposite: employee experiences in a Canadian setting
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-11, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.704123?ai=1lir&mi=3s94u5&af=R
Stroke family caregivers’ support needs change across the care continuum: a qualitative study using the timing it right framework
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-10, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.691937?ai=1lir&mi=3s94u5&af=R
Lunes, Oktubre 22, 2012
Multi-professional and multi-dimensional group education – a key to action in elderly persons
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-9, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.697249?ai=1lir&mi=3s94u5&af=R
Life Serves at U S Olympic Track and Field Trials
Life Chiropractic News
MARIETTA, GA. -- Four Life University chiropractic sport science students recently traveled to famed Hayward Field in Eugene, OR., to assist Olympic hopefuls competing in the 2012 U.S. Olympic Trials in Track and Field (held June 21 through July 1).
Students Oscar Adorno-Bruno (31), Gregory Busby (25), Michael Drzewieki...
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MARIETTA, GA. -- Four Life University chiropractic sport science students recently traveled to famed Hayward Field in Eugene, OR., to assist Olympic hopefuls competing in the 2012 U.S. Olympic Trials in Track and Field (held June 21 through July 1).
Students Oscar Adorno-Bruno (31), Gregory Busby (25), Michael Drzewieki...
This is a planetchiropractic content summary feed. Visit www.planetchiropractic.com for complete content, links, and related media. - Cheers!
Read More Here Discover More Here Learn More Here Click This Link
Type 2 diabetes may increase the risk of Barrett’s esophagus
Patients with Type 2 Diabetes may face an increased risk for Barrett’s Esophagus (BE), regardless of other risk factors including smoking, alcohol consumption, obesity and gastroesophageal reflux disease (GERD), according to research unveiled today at the American College of Gastroenterology’s (ACG) 77th Annual Scientific meeting in Las Vegas.
The study, “Diabetes Mellitus Increases the Risk of Barrett’s Esophagus: Results from A Large Population Based Control Case Study,” suggests that, “if you have diabetes, your risk for Barrett’s esophagus (BE) may be almost doubled ,” said co-investigator, Prasad G. Iyer, M.D., of the Mayo Clinic College of Medicine. He said this risk may be higher in men with diabetes likely because men tend to carry more fat in the abdomen compared to women who tend to carry weight around the hips and thighs.
Type 2 diabetes is the most is the most form of diabetes, with millions of Americans living with the disease. Barrett’s esophagus is a condition in which the tissue lining the esophagus is replaced by tissue that is similar to the lining of the intestine. No signs or symptoms are associated with Barrett’s esophagus but it is commonly found in people with GERD. About 5 to 10 percent of patients with chronic GERD will develop Barrett’s esophagus.
Performing a population-based control study using the United Kingdom’s General Practice Research Database (GPRD) (a primary care database containing more than 8 million patients), the researchers identified 14,245 Barrett’s esophagus cases and 70,361 controls without Barrett’s esophagus.
The study, “Diabetes Mellitus Increases the Risk of Barrett’s Esophagus: Results from A Large Population Based Control Case Study,” suggests that, “if you have diabetes, your risk for Barrett’s esophagus (BE) may be almost doubled ,” said co-investigator, Prasad G. Iyer, M.D., of the Mayo Clinic College of Medicine. He said this risk may be higher in men with diabetes likely because men tend to carry more fat in the abdomen compared to women who tend to carry weight around the hips and thighs.
Type 2 diabetes is the most is the most form of diabetes, with millions of Americans living with the disease. Barrett’s esophagus is a condition in which the tissue lining the esophagus is replaced by tissue that is similar to the lining of the intestine. No signs or symptoms are associated with Barrett’s esophagus but it is commonly found in people with GERD. About 5 to 10 percent of patients with chronic GERD will develop Barrett’s esophagus.
Performing a population-based control study using the United Kingdom’s General Practice Research Database (GPRD) (a primary care database containing more than 8 million patients), the researchers identified 14,245 Barrett’s esophagus cases and 70,361 controls without Barrett’s esophagus.
Source: http://www.health.am/db/more/type-2-diabetes-may-increase-the-risk/
Researchers Identify Changes in Cholesterol Metabolic Pathways
A new study from the Virginia Commonwealth University School of Medicine has identified molecular changes responsible for abnormal cholesterol production and metabolism in the livers of patients with a common liver condition, and these changes may explain the severity of a patient’s liver disease and risks to their heart health.
It is estimated that a third of Americans have a fatty liver. Nonalcoholic fatty liver disease is a very common liver condition. Nonalcoholic steatohepatitis, or NASH, the more aggressive form of nonalcoholic fatty liver disease, is associated with increased cardiac risk and liver-related mortality.
The VCU findings may provide researchers with potential new targets for treatment and also allow clinicians to further refine how they assess cardiovascular risk and develop ways to reduce it in individuals with a more aggressive form of nonalcoholic fatty liver disease called nonalcoholic steatohepatitis, or NASH.
It is estimated that a third of Americans have a fatty liver. Nonalcoholic fatty liver disease is a very common liver condition. Nonalcoholic steatohepatitis, or NASH, the more aggressive form of nonalcoholic fatty liver disease, is associated with increased cardiac risk and liver-related mortality.
The VCU findings may provide researchers with potential new targets for treatment and also allow clinicians to further refine how they assess cardiovascular risk and develop ways to reduce it in individuals with a more aggressive form of nonalcoholic fatty liver disease called nonalcoholic steatohepatitis, or NASH.
Source: http://www.health.am/cholesterol/more/changes-in-cholesterol-metabolic-pathways/
A systematic review of disability awareness interventions for children and youth
Disability and Rehabilitation, Volume 0, Issue 0, Page 1-24, Early Online.
Source: http://informahealthcare.com/doi/abs/10.3109/09638288.2012.702850?ai=1lir&mi=3s94u5&af=R
Recovering ‘bodyguard’ cells in pancreas may restore insulin production in diabetics
The key to restoring production of insulin in type I diabetic patients, previously known as juvenile diabetes, may be in recovering the population of protective cells known T regulatory cells in the lymph nodes at the “gates” of the pancreas, a new preclinical study published online October 8 in Cellular & Molecular Immunology by researchers in the Department of Bioscience Technologies at Thomas Jefferson University suggests.
Tatiana D. Zorina, M.D., Ph.D., an Assistant Professor in the Department of Bioscience Technologies, Jefferson School of Health Professions, and colleagues addressed a question of whether type I diabetic patients’ own beta cells, which produce insulin, could recover/regenerate if protected from autoimmune cells. If successful, such an approach would promote the patient’s own insulin production without need for its supplementation by insulin injections or beta cell transplantation from the cadaver organ donors.
Type 1 diabetes is usually diagnosed in children and young adults. As many as 3 million Americans have type 1 diabetes, and each year, more than 15,000 children and 15,000 adults are diagnosed in the United States. Type 1 diabetes is a disease that occurs as a result of destruction of beta cells producing insulin by autoimmune cells. The resulting lack of insulin, which is needed to metabolize/process the sugar, leads to increased levels of sugar in the blood and all clinical symptoms of type 1 diabetes. The only currently available therapies for type 1 diabetes patients are based on insulin provision (by different means).
In healthy people, the autoimmune cells are also present, but insulin-producing beta cells (residing in the pancreas) are normally protected from their attack by the T regulatory cells, or Treg cells. Treg cells confront and disable the autoimmune cells in the pancreatic lymph nodes (which play a role of the gates of the pancreas) and thus protect beta cells in the pancreas from being destroyed.
Tatiana D. Zorina, M.D., Ph.D., an Assistant Professor in the Department of Bioscience Technologies, Jefferson School of Health Professions, and colleagues addressed a question of whether type I diabetic patients’ own beta cells, which produce insulin, could recover/regenerate if protected from autoimmune cells. If successful, such an approach would promote the patient’s own insulin production without need for its supplementation by insulin injections or beta cell transplantation from the cadaver organ donors.
Type 1 diabetes is usually diagnosed in children and young adults. As many as 3 million Americans have type 1 diabetes, and each year, more than 15,000 children and 15,000 adults are diagnosed in the United States. Type 1 diabetes is a disease that occurs as a result of destruction of beta cells producing insulin by autoimmune cells. The resulting lack of insulin, which is needed to metabolize/process the sugar, leads to increased levels of sugar in the blood and all clinical symptoms of type 1 diabetes. The only currently available therapies for type 1 diabetes patients are based on insulin provision (by different means).
In healthy people, the autoimmune cells are also present, but insulin-producing beta cells (residing in the pancreas) are normally protected from their attack by the T regulatory cells, or Treg cells. Treg cells confront and disable the autoimmune cells in the pancreatic lymph nodes (which play a role of the gates of the pancreas) and thus protect beta cells in the pancreas from being destroyed.
Source: http://www.health.am/db/more/restore-insulin-production-in-diabetics/
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